Alere INRatio®2 PT/INR Monitoring - Clinical Performance

Proven Performance You Can Depend On

Since the precision of PT/INR results can influence therapy decisions and patient outcomes, clinicians should select an INR monitoring device that provides precise results.

For the last five years, the Alere INRatio®2 PT/INR Monitoring System has been the preferred choice by physicians in PT/INR testing at the point-of-care.1 Why? Because of its outstanding performance, 2-level on-board quality control system, 1-drop sample size, and the protective individual foil-wrapped test strips preferred by cardiologists.2

Data You Can Believe

No two methodologies will produce identical results. In fact, no single technology will provide the same result each time.

The difference plot shown below compares the Alere INRatio®2 PT/INR System capillary results to Sysmex CA-560/Dade Innovin® results. This figure shows that 97% of the results in the therapeutic interval of 2.0 to 4.5 are within the ±30% interval compared to 90% requirement per ISO guideline.The expectation is that the differences will not be clinically significant.

Each lab may claim to be correct. If the results fit the clinical assessment and the patient uses the same lab every time; then they can be properly managed regardless of method.

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Comparing instruments

The key is that you monitor patients using a single technology over time, rather than multiple technologies per patient.

These charts show the results of a three-way correlation study conducted at a customer site. Both the Alere INRatio®2 INR results and the other point-of-care (POC) method INR results compare well with the lab method. However, comparing the two POC methods, there are greater differences.

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Thick solid line is the linear regression best fit; think solid lines indicate ISO 17593:2007 POC INR 90% acceptance limts;4 dotted line is the line of identity (y = x).

Consider the data

All INR meters are designed to monitor patients over time, so there is other data to consider. If a patient has been trending on the edge of therapeutic for months and now with a different meter reads slightly higher, or lower, what is the clinical difference? Moving forward, a new result should continue to show the same trend, but at the newly established level. 

Alere™ Home Monitoring Service Program

Alere has developed an industry leading program to help healthcare professionals provide the highest quality anticoagulation management.

Call to talk to an Alere representative 1.866.408.1205!